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Biyobenzer İlaçlar

Yıl 2020, Cilt: 13 Sayı: 2, 34 - 42, 09.04.2021
https://doi.org/10.20854/bujse.874593

Öz

Biyobenzer ilaçlar, saflık, güvenlik ve etkinlik açısından referans kaynağından klinik olarak anlamlı farklılıklara sahip olmayan lisanslı biyolojiklere (referans biyolojikler) oldukça benzer olduğu gösterilen biyolojikler olarak tanımlanmaktadır. Biyobenzerler, biyolojik kaynaklı ilaçlarla tedavisi olan hastalıklar açısından alternatif ilaçlar olarak üretilmektedir. Bu sayede kanser gibi spesifik hastalıklara yönelik tedaviler çeşitlilik kazanmaktadır. Örneğin meme kanseri için kullanılan biyobenzerler geliştirildikçe gelecekte bu hastalığın tedavilerine erişilebilirlik artacaktır ve bu gelişmeler de anti-HER2 ve anti-VEGF tedavisinin daha yaygın kullanımına olanak sağlayacaktır. Meme kanseri tedavisinde kullanılan Trastuzumab için, Avrupa patenti 2014'te, ABD patenti 2019'da sona ermiştir. Patent sürelerinin dolması bu biyobenzer ilaçların geliştirilmesini hızlandırmıştır. Bu derlemede öncelikle biyobenzerler hakkında genel bilgiler aktarılmış ve Göğüs/Meme kanseri için kullanılan biyobenzerler hakkında ayrıntılı tartışma gerçekleştirilmiştir.

Kaynakça

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Toplam 50 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Mühendislik
Bölüm Makaleler
Yazarlar

Çağla Küçük Bu kişi benim

Özlem Ateş Duru 0000-0001-8961-5113

Esra Mutlu

Hande Kazak Sarilmiser

Yayımlanma Tarihi 9 Nisan 2021
Yayımlandığı Sayı Yıl 2020 Cilt: 13 Sayı: 2

Kaynak Göster

APA Küçük, Ç., Ateş Duru, Ö., Mutlu, E., Kazak Sarilmiser, H. (2021). Biyobenzer İlaçlar. Beykent Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 13(2), 34-42. https://doi.org/10.20854/bujse.874593
AMA Küçük Ç, Ateş Duru Ö, Mutlu E, Kazak Sarilmiser H. Biyobenzer İlaçlar. BUJSE. Nisan 2021;13(2):34-42. doi:10.20854/bujse.874593
Chicago Küçük, Çağla, Özlem Ateş Duru, Esra Mutlu, ve Hande Kazak Sarilmiser. “Biyobenzer İlaçlar”. Beykent Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 13, sy. 2 (Nisan 2021): 34-42. https://doi.org/10.20854/bujse.874593.
EndNote Küçük Ç, Ateş Duru Ö, Mutlu E, Kazak Sarilmiser H (01 Nisan 2021) Biyobenzer İlaçlar. Beykent Üniversitesi Fen ve Mühendislik Bilimleri Dergisi 13 2 34–42.
IEEE Ç. Küçük, Ö. Ateş Duru, E. Mutlu, ve H. Kazak Sarilmiser, “Biyobenzer İlaçlar”, BUJSE, c. 13, sy. 2, ss. 34–42, 2021, doi: 10.20854/bujse.874593.
ISNAD Küçük, Çağla vd. “Biyobenzer İlaçlar”. Beykent Üniversitesi Fen ve Mühendislik Bilimleri Dergisi 13/2 (Nisan 2021), 34-42. https://doi.org/10.20854/bujse.874593.
JAMA Küçük Ç, Ateş Duru Ö, Mutlu E, Kazak Sarilmiser H. Biyobenzer İlaçlar. BUJSE. 2021;13:34–42.
MLA Küçük, Çağla vd. “Biyobenzer İlaçlar”. Beykent Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, c. 13, sy. 2, 2021, ss. 34-42, doi:10.20854/bujse.874593.
Vancouver Küçük Ç, Ateş Duru Ö, Mutlu E, Kazak Sarilmiser H. Biyobenzer İlaçlar. BUJSE. 2021;13(2):34-42.