Araştırma Makalesi
BibTex RIS Kaynak Göster

Evaluation of Histopathological Findings in Patients Undergoing Laparoscopic Sleeve Gastrectomy Specimens

Yıl 2020, Cilt: 42 Sayı: 5, 504 - 509, 15.09.2020
https://doi.org/10.20515/otd.551907

Öz

Laparoscopic
sleeve gastrectomy (LSG) is a common surgical therapeuti coption in patients
with morbid obesity that debate about the value of routine histopathologi cal examination
of LSG. Also the effect of Helicobacterpylori colonization of the stomach of
patient sunder going LSG is unclear. Ouraim is to analyze there sults of
histopathological examination of LSG specimensan didentify the prevalence of
Helicobacterpylori. This study is a retrospective study of the patients who underwent
LSG for the treatment of morbid obesity in our hospital between 
2014-2018. Sex, age, histopathologi
calfindings in the surgical specimens and prevalenceof
  Helicobacterpylori(HP) infection were
analyzed. Gastricspecimens of a total of 110 patients( 90females, 20 males;
meanage 38 ± 11.9years)were analyzed in this study.Themost common
histopathological findings in the surgical specimens were chronicin
  active gastritis (57.3%,n=63),chronic active
gastritis ( 34.5%, n= 38),intestinal metaplasia (6.4%, n=7), fundic gland polyp
(1.8%,n=2), parietal cellhy pertrophia (0.9 %, n=1). Fourty eight
  (43.6%) patients were foundto be HP positive.
There was statistically significant correlation between gastritis and HP
infections. The majority of patients who underwent LSG had pathological
findings in resected specimens.It is concluded that the pathological evaluation
of the LSG specimens is necessary because of the clinical significance of HP
infection and intestinal metaplasia.

Kaynakça

  • 1. Yardımcı E, Bozkurt S, Lutfullah Baskoy, Bektasoğlu HK, Gecer MO, Yigman S, Akbulut H, Coskun H. Rare entities of histopathological findings in 755 sleeve gastrectomy cases: a synopsis of preoperative endoscopy findings and histological evalution of the specimens. Obesity Surgery. 2018; 28: 1289-1295.
  • 2. Doğan U, Suren D, Oruç MT, Gokay AA, Mayır B, Cakır T, Aslaner A, Oner OZ, Bulbuller N. Spectrum of gastric histopathologies in morbidly obese Turkish patients undergoing laparoscopic sleeve gastrectomy. European Review for Medical and Pharmacological Sciences. 2017; 21: 5430-5436.
  • 3. Hansen SK, Pottorf BJ, Hollis HW, Rogers JL, Husain FA. Is it necessary to perform full pathologic review of all gastric remnants following sleeve gastrectomy? The American Journal of Surgery. 2017; 214: 1151-1155.
  • 4. Safaan T, Bashah M, Ansari WE, Karam M. Histopathological changes in laparoscopic sleeve gastrectomy specimens: Prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017; 27:1741-1749.
  • 5. Canil AM, Lossa A, Termine P, Caporilli D, Petrozza V, Silecchia G. Histopathological findings in patients undergoing laparoscopic sleeve gastrectomy. Obesity Surgery. 2018; 28: 1760-1765.
  • 6. Öner RİÖ, Özdaş S. Histopathological findings in morbid obese patients undergoing laparoscopic sleeve gastrectomy: Does H.pylori infection effective on pathological changes? Obesity Surgery. 2018; 28: 3136-3141.
  • 7. Demirbaş BH, Erdim A, Celikel C, Akbas G, Cingi A. Is it necessary to send the sleeve gastrectomy specimens to pathology? Surg Laparosc Endosc Percutan Tech. 2018
  • 8. Ohanessian SE, Rogers AM, Karamchandani DM. Spectrum of gastric histopathologies in severely obese American patients undergoing sleeve gastrectomy. Obes Surg. 2016; 26: 595-602.
  • Aljerian K. Histopathological findings in laparoscopic sleeve gastrectomy specimens from patients with obesity in Saudi Arabia. Gastroenterology research and practice 2

Laparoskopik Sleeve Gastrektomi Materyallerinde Histopatolojik Bulguların Değerlendirilmesi

Yıl 2020, Cilt: 42 Sayı: 5, 504 - 509, 15.09.2020
https://doi.org/10.20515/otd.551907

Öz

Laparoskopik
sleeve gastrektomi (LSG) morbid obezitede sık kullanılan bir tedavi yöntemi
olup, bu spesmenlerde rutin histopatolojik incelemenin değeri tartışmalıdır.
Ayrıca LSG yapılan hastalarda midedeki HP kolonizasyonunun etkisi
bilinmemektedir. Bu çalışmada amacımız LSG spesmenlerindeki histopatolojik inceleme
sonuçlarını değerlendirmek ve HP prevalansını belirlemektir. Bu çalışma
hastanemizde 2014-2018 yılları arasında morbid obezite nedenli LSG yapılan
hastaları içeren retrospektif bir çalışmadır. Yaş, cinsiyet, cerrahi
spesmenlerdeki histopatolojik bulgular ve HP infeksiyon prevalansı
değerlendirildi. Bu çalışmada 110 hastanın (90 kadın, 20 erkek; ortalama yaş 38
± 11.9 yıl) gastrik spesmeni incelendi. Cerrahi spesmende sık gözlenen
histopatolojik bulgular kronik inaktif gastrit (%57.3, n=63), kronik aktif
gastrit ( %34.5, n= 38) intestinal metaplazi (%6.4, n=7), minimal atrofi (%12.7,
n=14), fundik gland polip (%1.8,n=2), nöroendokrin hücre hiperplazisi
(%1.8’inde, n=2),  
pariyetal hücre
hipertrofisidir (%0.9 , n=1). Kırk sekiz hastada (%43.6) HP pozitifti. Gastrit
ve atrofi ile HP infeksiyonu arasında istatiksel olarak anlamlı korelasyon
saptandı p<0.001).
LSG
yapılan olguların çoğunda histopatolojik değişiklikler saptanmıştır. H.P infeksiyonu,
atrofi ve intestinal metaplazinin klinik önemi nedeniyle LSG spesmenlerinin histopatolojik
değerlendirmesinin gerekli olduğu sonucuna varılmıştır.

Kaynakça

  • 1. Yardımcı E, Bozkurt S, Lutfullah Baskoy, Bektasoğlu HK, Gecer MO, Yigman S, Akbulut H, Coskun H. Rare entities of histopathological findings in 755 sleeve gastrectomy cases: a synopsis of preoperative endoscopy findings and histological evalution of the specimens. Obesity Surgery. 2018; 28: 1289-1295.
  • 2. Doğan U, Suren D, Oruç MT, Gokay AA, Mayır B, Cakır T, Aslaner A, Oner OZ, Bulbuller N. Spectrum of gastric histopathologies in morbidly obese Turkish patients undergoing laparoscopic sleeve gastrectomy. European Review for Medical and Pharmacological Sciences. 2017; 21: 5430-5436.
  • 3. Hansen SK, Pottorf BJ, Hollis HW, Rogers JL, Husain FA. Is it necessary to perform full pathologic review of all gastric remnants following sleeve gastrectomy? The American Journal of Surgery. 2017; 214: 1151-1155.
  • 4. Safaan T, Bashah M, Ansari WE, Karam M. Histopathological changes in laparoscopic sleeve gastrectomy specimens: Prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017; 27:1741-1749.
  • 5. Canil AM, Lossa A, Termine P, Caporilli D, Petrozza V, Silecchia G. Histopathological findings in patients undergoing laparoscopic sleeve gastrectomy. Obesity Surgery. 2018; 28: 1760-1765.
  • 6. Öner RİÖ, Özdaş S. Histopathological findings in morbid obese patients undergoing laparoscopic sleeve gastrectomy: Does H.pylori infection effective on pathological changes? Obesity Surgery. 2018; 28: 3136-3141.
  • 7. Demirbaş BH, Erdim A, Celikel C, Akbas G, Cingi A. Is it necessary to send the sleeve gastrectomy specimens to pathology? Surg Laparosc Endosc Percutan Tech. 2018
  • 8. Ohanessian SE, Rogers AM, Karamchandani DM. Spectrum of gastric histopathologies in severely obese American patients undergoing sleeve gastrectomy. Obes Surg. 2016; 26: 595-602.
  • Aljerian K. Histopathological findings in laparoscopic sleeve gastrectomy specimens from patients with obesity in Saudi Arabia. Gastroenterology research and practice 2
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm ORİJİNAL MAKALELER / ORIGINAL ARTICLES
Yazarlar

Funda Canaz 0000-0002-5642-3876

Evrim Yılmaz Bu kişi benim 0000-0003-1937-8313

Özgül Paşaoğlu Bu kişi benim 0000-0002-0739-3199

Deniz Arık 0000-0003-0905-2731

Adnan Şahin 0000-0002-4933-420X

Yayımlanma Tarihi 15 Eylül 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 42 Sayı: 5

Kaynak Göster

Vancouver Canaz F, Yılmaz E, Paşaoğlu Ö, Arık D, Şahin A. Laparoskopik Sleeve Gastrektomi Materyallerinde Histopatolojik Bulguların Değerlendirilmesi. Osmangazi Tıp Dergisi. 2020;42(5):504-9.


13299        13308       13306       13305    13307  1330126978