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Diagnostic Approach to the Patients with Chest Pain

Yıl 2008, Cilt: 2 Sayı: 1, 280 - 285, 23.03.2008

Öz

Chest pain is one of the most frequent symptoms for which patients are evaluated in an emergency department. Chest pain is merely a symptom, not a diagnosis. Many medical problems can cause chest pain, and before the chest pain can be adequately treated, the actual underlying cause needs to be identified. The following is a list of the more common causes of chest pain, roughly in order of the frequency in which they are seen in the emergency room. Angina due to coronary artery disease, benign chest wall pain, anxiety or panic disorder, pneumonia, pleuritis, mitral valve prolapse, pericarditis, chest trauma, peptic ulcer, angina due to coronary artery spasm, angina due to cardiac syndrome X, aortic dissection. Some causes of chest pain require prompt medical attention, such as acute coronary syndromes tearing of the aorta, or pulmonary embolism. Because the cause of chest pain can range, from an ordinary, harmless muscle pull to serious cardiac complication ultimately leading to cardiac arrest. Coronary artery disease is so common and so dangerous that the symptom of chest pain should never be dismissed out of hand as being insignificant. Therefore, an accurate diagnosis is important in providing proper treatment to patients with chest pain. The diagnostic procedure in patients with acute chest pain should serve two major purpose: to quickly identify high risk patients quickly for the fast track and to delineate patients in whom there is little or no suspicion of a life-threatening disease. In this paper, the approach to chest pain was reviewed.

Kaynakça

  • 1. McCaig LF, Burt CW. National hospital ambulatory medical care survey: 2002 emergency department summary. Adv Data 2004;340:1-34.
  • 2. Antman EM, Anbe DT, Armstrong PW, et al. ACC /AHA guidelines for the management of patient with ST-elevation myocardial infarction; a report of the American College of Car-diology/American Heart Association Task Force on Practice Guidelines (Committe to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial infarction). J Am Coll Cardiol 2004;44:671-719.
  • 3. Amsterdam EA, Lewis WR, Kirk JD, Diercks DB, Turnipseed S. Acute ischemic syn- dromes. Chest pain center concept. Cardiol Clin 2002; 20:117-36.
  • 4. Gersh BJ, Braunwald E, Bonow RO. Chronic coronary artery desease. In: Braunwald E, Zipes DP, Libby P, editors. Heart Desease: A Textbook of Cardiovascuter Medicine. 6th. ed. Philadelphia: WB Saunders; 2001.p. 1272-7
  • 5. Everts B, Karlson BW, Wharborg P, Hedner T, Herlitz J. Localization of pain in suspected acute myocardial infarction in relation to final diagnosis, age and sex, and site and type of infarction. Heart Lung 1996; 25: 430-7
  • 6. Goldberg RJ, O’Donnell C, Yarzebski J, Bigelow C, Savageau J, Gore JM. Sex differ- ences in symptom presentation associated with acute myocardial infarction: A population-based perspective.Am Heart J 1998;136:189-95.
  • 7. Herlitz J, Richter A, Hjalmarson Ar, Hovgren C, Holmberg S, Bondestam E. Chest pain in acute myocardial infarction.A descriptive study according to subjective assesment and morphine requirement. Clin Cardiol 1986; 9:423-8.
  • 8. Hofgren C, Karlson BW, Gaston-Johanson F, Herlitz J. Word descriptors in suspected acute myocardial infarction.A comparison between patients with and without confirmed myocardial infarction.Heart Lung 1994; 40: 397-403.
  • 9. Braunwald E. Unstable angina: A classification. Circulation 1989; 80:410-4.
  • 10. Goldhaber SZ. Pulmonary embolism. In: Braunwald E, ed., Heart Disease. 6th ed. Philadelphia: W.B Saunders 2001; 1886-907.
  • 11. Lee TH, Rouan GW, Weisberg MC et al.Sen-sitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization. Ann Intern Med 1987; 106:181-6.
  • 12. Pope JH, Aufderheide TP, Ruthazer R et al. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med 2000; 342:1163-70.
  • 13. McCarthy BD, Beshansky JR, D’Agostino RB, Selker HP. Missed diagnoses of acute myocardial infarction in the emergency department: results from a multicenter study. Ann Emerg Med 1993; 22: 579-82.
  • 14. Galli M, Marcassa C. Risk stratification in unstable angina:should every patient undergo coronary angiography? Q J Nucl Med 1997; 41 (Suppl 1): 51-60.
  • 15. Yusuf S, Pearson M, Sterry H et al. The en-tery ECG in the early diagnosis and prognostic stratification of patients with suspected acute myocardial infarction. Eur Heart J 1984; 5: 690-6.
  • 16. Lee TH, Goldman L. Evaluation of the patient with acute chest pain. N Engl J Med 2000; 342:1187-95.
  • 17. Delborg M, Herlitz J, Emanuelsson H, Swed-berg K. Electrocardiographic changes during myocardial ischemia: difference between men and women. J Electrocardiol 1994; 29(Suppl): 42-5.
  • 18. Karlson BW, Herlitz J, Wiklund O, Richter A, Hjalmarson A. Early prediction of acute myocardial infarction from clinical history, exami-
  • nation and electrocardiogram in the emergency room. Am J Cardiol 1991; 68:171-5.
  • 19. Brush JE, Brand DA, Acampora D, Chalmer B, Wackers FJ. Use of the initial electrocardiogram to predict in-hospital complications of acute myocardial infarction. N Engl J Med 1985; 312:1137-41.
  • 20. Herlitz J, Karlson BW, Lindqvist J, Sjölin M. Predictors and mode of death over 5 years amongst patients admitted to the emergency department with acute chest pain or other symptoms raising suspicion of acute myocardial infarction. J Intern Med 1998; 243: 41-8
  • 21. Karlson BW, Herlitz J, Hallgren P, Liljeqvist J-A, Oden A, Hjalmarson A. Emergency room prediction of mortality and severe complications in patients with suspected acute myocardial infarction. Eur Heart J 1994; 15: 1558-65.
  • 22. de Winter RJ, Koster RW, Sturk A, Sanders GT. Value of myoglobin, troponin T, and CK-MB mass in ruling out an acute myocardial infarction in the emergency room. Circulation 1995;92:3401-7.
  • 23. Puleo PR, Meyer D, Wathen C et al. Use of a rapid assay of subforms of creatine kinase MB to diagnose or rule out acute myocardial infarction. N Engl J Med 1994;331:561-6.
  • 24. Newby LK, Kaplan AL, Granger BB, Sedor F, Calif RM, Ohman EM. Comparison of cardiac troponin T versus creatinine kinase MB for risk stratification in a chest pain evaluation unit. Am J Cardiol 2000; 85: 801-5.
  • 25. Buenger RE. Five thousand acute care/emer-gency department chest radiographs:compar-ison of requisitions with radiographic findings. J Emerg Med 1988; 6:197-202.
  • 26. Wackers FJ, Lie KI, Liem KL et al. Potential value of thallium-201 scintigraphy as a means of selecting patients for the coronary care unit. Br Heart J 1979; 41:111-7.
  • 27. Van der Wiecken L, Kan G, Belfer AJ et al. Thallium-201 scanning to decide CCU admission in patients with non-diagnostic electrocardiograms. Int J Cardiol 1983; 4: 285-95
  • 28. de Zwaan C, Cheriex EC, Braat SH et al. Improvement of systolic and diastolic left ventricular wall motion by serial echocardiograms in selected patients treated for unstable angina. Am Heart J 1991;121:789-97.
  • 29. Jeroudi MO, Cherif J, Habib G et al. Prolonged wall motion abnormalities after chest pain at rest in patients with unstable angina: a possible manifestation of myocardial stunning. Am Heart J 1994; 127:1241-50.
  • 30. Peels CH, Visser CA, Kupper AJ et al. Usefulness of two-dimensional echocardiography for immediate detection of myocardial ischemia in the emergency room. Am J Cardiol 1990; 65: 687-91.
  • 31. Fleischmann KE, Lee R, Come P et al. Impact of valvular regurgitation and ventricular dysfunction on long-term survival in patients with chest pain. Am J Cardiol 1997; 80: 1266-72.
  • 32. Armstrong WF, Bach DS, Carey LM, Froelich J, Lowell M, Kazerooni E. Clinical and echocardiographic findings in patients with suspected acute aortic dissection. Am Heart J 1998;136:1051-60.
  • 33. Giannuzzi P, Imparato A, Temporelli PL et al. Doppler-derived mitral deceleration time of early filling as a strong predictor of pulmonary capillary wedge pressure in post-infarction patients with left ventricular systolic dysfunction. J Am Coll Cardiol 1994; 23:1630-7.

Göğüs Ağrılı Hastaya Tanısal Yaklaşım

Yıl 2008, Cilt: 2 Sayı: 1, 280 - 285, 23.03.2008

Öz

Göğüs ağrısı acil servislerde hastaların en sık şikayet ettikleri semptomlardan biridir. Göğüs ağrısı bir tanı olmayıp sadece bir semptomdur. Pek çok tıbbi durum göğüs ağnsına yol açabilir ve yeterli bir şekilde tedavi edilmeden önce altta yatan gerçek nedenin aydınlatılması gereklidir. Hastanelerin acil servis bölümlerine başvuran göğüs ağrılı hastaların sıklık sırasına göre kabaca en yaygın göğüs ağrısı nedenleri şu şekilde listelenebilir. Koroner arter hastalığına bağlı göğüs ağrısı, benign göğüs duvarı ağrısı, anksiyete, panik bozukluk, pnömoni veya plörite bağlı göğüs ağrıları, mitral kapak prolapsusu, perikardit, künt göğüs travması, peptik ülsere bağlı göğüs ağnları, koroner arter spazmı, kardiyak sendrom X ve aort diseksiyonuna bağlı göğüs ağrısı. Aort diseksiyonu, pulmoner emboli ve akut koroner sendrom gibi bazı durumlar acil değerlendirme ve tedavi gerektirir. Göğüs ağrısının nedenleri önemsiz bir kas hastalığından ciddi komplikasyonlann olduğu kardiyak arreste kadar geniş bir yelpaze ile karşımıza çıkar. Koroner arter hastalığına bağlı göğüs ağrısı, kesinlikle atlanmaması gereken göğüs ağrısının en tehlikeli ve en yaygın formudur. Bu nedenle göğüs ağrısı olan hastaların doğru teşhis ve uygun tedavi edilmeleri önemlidir. Akut göğüs ağrısına tanısal yaklaşımda iki ana hedef olmalıdır: yüksek riskli hastaların çok hızlı bir şekilde saptanıp tedavisinin planlanması ve hayati tehlikesi çok az olan veya hayati tehlikesi bulunmayan hastaların belirlenmesidir. Bu yazıda göğüs ağrısına yaklaşım incelenmiştir.

Kaynakça

  • 1. McCaig LF, Burt CW. National hospital ambulatory medical care survey: 2002 emergency department summary. Adv Data 2004;340:1-34.
  • 2. Antman EM, Anbe DT, Armstrong PW, et al. ACC /AHA guidelines for the management of patient with ST-elevation myocardial infarction; a report of the American College of Car-diology/American Heart Association Task Force on Practice Guidelines (Committe to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial infarction). J Am Coll Cardiol 2004;44:671-719.
  • 3. Amsterdam EA, Lewis WR, Kirk JD, Diercks DB, Turnipseed S. Acute ischemic syn- dromes. Chest pain center concept. Cardiol Clin 2002; 20:117-36.
  • 4. Gersh BJ, Braunwald E, Bonow RO. Chronic coronary artery desease. In: Braunwald E, Zipes DP, Libby P, editors. Heart Desease: A Textbook of Cardiovascuter Medicine. 6th. ed. Philadelphia: WB Saunders; 2001.p. 1272-7
  • 5. Everts B, Karlson BW, Wharborg P, Hedner T, Herlitz J. Localization of pain in suspected acute myocardial infarction in relation to final diagnosis, age and sex, and site and type of infarction. Heart Lung 1996; 25: 430-7
  • 6. Goldberg RJ, O’Donnell C, Yarzebski J, Bigelow C, Savageau J, Gore JM. Sex differ- ences in symptom presentation associated with acute myocardial infarction: A population-based perspective.Am Heart J 1998;136:189-95.
  • 7. Herlitz J, Richter A, Hjalmarson Ar, Hovgren C, Holmberg S, Bondestam E. Chest pain in acute myocardial infarction.A descriptive study according to subjective assesment and morphine requirement. Clin Cardiol 1986; 9:423-8.
  • 8. Hofgren C, Karlson BW, Gaston-Johanson F, Herlitz J. Word descriptors in suspected acute myocardial infarction.A comparison between patients with and without confirmed myocardial infarction.Heart Lung 1994; 40: 397-403.
  • 9. Braunwald E. Unstable angina: A classification. Circulation 1989; 80:410-4.
  • 10. Goldhaber SZ. Pulmonary embolism. In: Braunwald E, ed., Heart Disease. 6th ed. Philadelphia: W.B Saunders 2001; 1886-907.
  • 11. Lee TH, Rouan GW, Weisberg MC et al.Sen-sitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization. Ann Intern Med 1987; 106:181-6.
  • 12. Pope JH, Aufderheide TP, Ruthazer R et al. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med 2000; 342:1163-70.
  • 13. McCarthy BD, Beshansky JR, D’Agostino RB, Selker HP. Missed diagnoses of acute myocardial infarction in the emergency department: results from a multicenter study. Ann Emerg Med 1993; 22: 579-82.
  • 14. Galli M, Marcassa C. Risk stratification in unstable angina:should every patient undergo coronary angiography? Q J Nucl Med 1997; 41 (Suppl 1): 51-60.
  • 15. Yusuf S, Pearson M, Sterry H et al. The en-tery ECG in the early diagnosis and prognostic stratification of patients with suspected acute myocardial infarction. Eur Heart J 1984; 5: 690-6.
  • 16. Lee TH, Goldman L. Evaluation of the patient with acute chest pain. N Engl J Med 2000; 342:1187-95.
  • 17. Delborg M, Herlitz J, Emanuelsson H, Swed-berg K. Electrocardiographic changes during myocardial ischemia: difference between men and women. J Electrocardiol 1994; 29(Suppl): 42-5.
  • 18. Karlson BW, Herlitz J, Wiklund O, Richter A, Hjalmarson A. Early prediction of acute myocardial infarction from clinical history, exami-
  • nation and electrocardiogram in the emergency room. Am J Cardiol 1991; 68:171-5.
  • 19. Brush JE, Brand DA, Acampora D, Chalmer B, Wackers FJ. Use of the initial electrocardiogram to predict in-hospital complications of acute myocardial infarction. N Engl J Med 1985; 312:1137-41.
  • 20. Herlitz J, Karlson BW, Lindqvist J, Sjölin M. Predictors and mode of death over 5 years amongst patients admitted to the emergency department with acute chest pain or other symptoms raising suspicion of acute myocardial infarction. J Intern Med 1998; 243: 41-8
  • 21. Karlson BW, Herlitz J, Hallgren P, Liljeqvist J-A, Oden A, Hjalmarson A. Emergency room prediction of mortality and severe complications in patients with suspected acute myocardial infarction. Eur Heart J 1994; 15: 1558-65.
  • 22. de Winter RJ, Koster RW, Sturk A, Sanders GT. Value of myoglobin, troponin T, and CK-MB mass in ruling out an acute myocardial infarction in the emergency room. Circulation 1995;92:3401-7.
  • 23. Puleo PR, Meyer D, Wathen C et al. Use of a rapid assay of subforms of creatine kinase MB to diagnose or rule out acute myocardial infarction. N Engl J Med 1994;331:561-6.
  • 24. Newby LK, Kaplan AL, Granger BB, Sedor F, Calif RM, Ohman EM. Comparison of cardiac troponin T versus creatinine kinase MB for risk stratification in a chest pain evaluation unit. Am J Cardiol 2000; 85: 801-5.
  • 25. Buenger RE. Five thousand acute care/emer-gency department chest radiographs:compar-ison of requisitions with radiographic findings. J Emerg Med 1988; 6:197-202.
  • 26. Wackers FJ, Lie KI, Liem KL et al. Potential value of thallium-201 scintigraphy as a means of selecting patients for the coronary care unit. Br Heart J 1979; 41:111-7.
  • 27. Van der Wiecken L, Kan G, Belfer AJ et al. Thallium-201 scanning to decide CCU admission in patients with non-diagnostic electrocardiograms. Int J Cardiol 1983; 4: 285-95
  • 28. de Zwaan C, Cheriex EC, Braat SH et al. Improvement of systolic and diastolic left ventricular wall motion by serial echocardiograms in selected patients treated for unstable angina. Am Heart J 1991;121:789-97.
  • 29. Jeroudi MO, Cherif J, Habib G et al. Prolonged wall motion abnormalities after chest pain at rest in patients with unstable angina: a possible manifestation of myocardial stunning. Am Heart J 1994; 127:1241-50.
  • 30. Peels CH, Visser CA, Kupper AJ et al. Usefulness of two-dimensional echocardiography for immediate detection of myocardial ischemia in the emergency room. Am J Cardiol 1990; 65: 687-91.
  • 31. Fleischmann KE, Lee R, Come P et al. Impact of valvular regurgitation and ventricular dysfunction on long-term survival in patients with chest pain. Am J Cardiol 1997; 80: 1266-72.
  • 32. Armstrong WF, Bach DS, Carey LM, Froelich J, Lowell M, Kazerooni E. Clinical and echocardiographic findings in patients with suspected acute aortic dissection. Am Heart J 1998;136:1051-60.
  • 33. Giannuzzi P, Imparato A, Temporelli PL et al. Doppler-derived mitral deceleration time of early filling as a strong predictor of pulmonary capillary wedge pressure in post-infarction patients with left ventricular systolic dysfunction. J Am Coll Cardiol 1994; 23:1630-7.
Toplam 34 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri (Diğer)
Bölüm Derlemeler
Yazarlar

Murat Akçay

Yayımlanma Tarihi 23 Mart 2008
Yayımlandığı Sayı Yıl 2008 Cilt: 2 Sayı: 1

Kaynak Göster

APA Akçay, M. (2008). Göğüs Ağrılı Hastaya Tanısal Yaklaşım. Türk Tıp Dergisi, 2(1), 280-285.

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